Russell A DeBose-Boyd Selected Research

Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)

1/2019	Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice.
1/2017	Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver.
11/2013	Geranylgeraniol suppresses the viability of human DU145 prostate carcinoma cells and the level of HMG CoA reductase.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Russell A DeBose-Boyd Research Topics

Disease

5	of Schnyder Crystalline Corneal Dystrophy 01/2020 - 03/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 06/2016
2	Neoplasms (Cancer) 01/2018 - 11/2013
2	Hypoxia (Hypoxemia) 01/2017 - 09/2007
1	Atherosclerosis 06/2016
1	Eye Diseases (Eye Disease) 01/2016
1	Carcinoma (Carcinomatosis) 11/2013
1	Prostatic Neoplasms (Prostate Cancer) 11/2013

Drug/Important Bio-Agent (IBA)

6	CholesterolIBA 01/2019 - 09/2007
3	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 01/2019 - 11/2013
3	Oxidoreductases (Dehydrogenase)IBA 01/2018 - 09/2007
3	SterolsIBA 06/2016 - 09/2007
2	Insulin (Novolin)FDA Link 01/2018 - 01/2017
2	Oxygen (Dioxygen)IBA 01/2017 - 09/2007
2	Transcription Factors (Transcription Factor)IBA 01/2017 - 09/2007
1	Dietary CholesterolIBA 01/2021
1	geranylgeranyl pyrophosphate (geranylgeranyl diphosphate)IBA 01/2020
1	menatetrenoneIBA 01/2020
1	Dimethylallyltranstransferase (Dimethylallyltransferase)IBA 01/2020
1	Vitamin K 2 (Vitamin K2)IBA 01/2020
1	LipidsIBA 01/2018
1	Messenger RNA (mRNA)IBA 01/2017
1	geranylgeraniolIBA 11/2013
1	DiterpenesIBA 11/2013
1	LanosterolIBA 09/2007
1	lanostenolIBA 09/2007
1	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA 09/2007

Therapy/Procedure

2	Therapeutics 01/2021 - 11/2013
1	Chemoprevention 11/2013